The effect of ultrasound machine settings on CRL/NT biases

A review of the impact of installing new ultrasound machines, emphasising the importance of optimising machine settings on a task-specific basis

Published on March 1, 2024

The NHS fetal anomaly screening programme (FASP) requires equal access to uniform and quality-assured screening to be offered to all eligible pregnant women in England. National policy is to offer screening to assess the chance of the baby being born with Down's syndrome (Trisomy 21), Edwards' syndrome (T18), and Patau's syndrome (T13). The test of choice for both singleton and twin pregnancies is the combined test1. If a woman accepts the offer of screening, the eligibility criteria for the combined test is when the baby's crown rump length (CRL) measurement is between 45.0mm and 84.0mm.

Screening is different to diagnosis as it usually only gives an indication of the chance of having the condition screened for. This is why screening results are given as lower or higher chance. Screening tests are not perfect and some people with a higher chance result will not...

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